Antithrombotic effect of beta,beta'-monochloromethylene diadenosine 5',5"'-P1,P4-tetraphosphate.

The feasibility of using beta,beta'-monochloromethylene diadenosine 5',5"'-P1,P4-tetraphosphate (AppCHCl-ppA) as an antithrombotic agent was studied in a rabbit intracarotid cannula thrombosis model previously shown to be sensitive to antiplatelet agents. This analogue, having a P-C-P bridge in plac...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kim, B K, Zamecnik, P, Taylor, G, Guo, M J, Blackburn, G M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.11056
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