Threonine 32 (Thr32) of FoxO3 is critical for TGF-β-induced apoptosis via Bim in hepatocarcinoma cells

Transforming growth factor-β (TGF-β) exerts apoptotic effects on various types of malignant cells, including liver cancer cells. However, the precise mechanisms by which TGF-β induces apoptosis remain poorly known. In the present study, we have showed that threonine 32 (Thr32) residue of FoxO3 is cr...

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Bibliographic Details
Published in:Protein Cell
Main Authors: Zhao, Xiangxuan, Liu, Yong, Du, Lei, He, Leya, Ni, Biyun, Hu, Junbo, Zhu, Dahai, Chen, Quan
Format: Artigo
Language:Inglês
Published: Higher Education Press 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312761/
https://ncbi.nlm.nih.gov/pubmed/25503443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-014-0121-5
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