Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel Fos/FoxO1/Stat3-Bim axis

Mechanical ventilation (MV) is a life-saving measure in many critically ill patients. However, prolonged MV results in diaphragm dysfunction that contributes to the frequent difficulty in weaning patients from the ventilator. The molecular mechanisms underlying ventilator-induced diaphragm dysfuncti...

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Detalhes bibliográficos
Main Authors: Tang, Huibin, Lee, Myung, Budak, Murat T., Pietras, Nicole, Hittinger, Scott, Vu, Michael, Khuong, Andy, Hoang, Chuong D., Hussain, Sabah N. A., Levine, Sanford, Shrager, Joseph B.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157683/
https://ncbi.nlm.nih.gov/pubmed/21597002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-183798
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