Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells

BACKGROUND: Melatonin induces apoptosis in many different cancer cell lines, including hepatocellular carcinoma cells. However, the responsible pathways have not been clearly elucidated. A member of the forkhead transcription factors' family, FoxO3a, has been implicated in the expression of the...

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Detalhes bibliográficos
Main Authors: Carbajo-Pescador, S, Steinmetz, C, Kashyap, A, Lorenz, S, Mauriz, J L, Heise, M, Galle, P R, González-Gallego, J, Strand, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Genetics & Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566813/
https://ncbi.nlm.nih.gov/pubmed/23257900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.563
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