Palmitate induces fat accumulation via repressing FoxO1-mediated ATGL-dependent lipolysis in HepG2 hepatocytes

Obesity is closely associated with non-alcoholic fatty liver disease (NAFLD), and elevated serum palmitate is the link between obesity and excessive hepatic lipid accumulation. Forkhead box O-1 (FoxO1) is one of the FoxO family members of transcription factors and can stimulate adipose triglyceride...

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Publicado en:PLoS One
Autores principales: Zhao, Naiqian, Tan, Huiwen, Wang, Li, Han, Le, Cheng, Yanli, Feng, Ying, Li, Ting, Liu, Xiaoling
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810308/
https://ncbi.nlm.nih.gov/pubmed/33449950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243938
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