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Allosteric Activation of the 5-HT(3)AB Receptor by mCPBG
The 5-HT(3)AB receptor contains three A and two B subunits in an A-A-B-A-B order. However, serotonin function at the 5-HT(3)AB receptor has been shown to depend solely on the A-A interface present in the homomeric receptor. Using mutations at sites on both the primary (E122) and complementary (Y146)...
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| Publicat a: | Neuropharmacology |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312754/ https://ncbi.nlm.nih.gov/pubmed/25541413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.12.018 |
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