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Dysfunctional HIV-specific CD8(+) T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis

Decreased human immunodeficiency virus (HIV)-specific CD8(+) T cell proliferation is a hallmark of chronic infection, but the mechanisms of decline are unclear. We analyzed gene expression profiles from antigen-stimulated HIV-specific CD8(+) T cells from patients with controlled and uncontrolled inf...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunity
Egile Nagusiak: Gaiha, Gaurav D., McKim, Kevin J., Woods, Matthew, Pertel, Thomas, Rohrbach, Janine, Barteneva, Natasha, Chin, Christopher R, Liu, Dongfang, Soghoian, Damien Z, Cesa, Kevin, Wilton, Shannon, Waring, Michael T., Chicoine, Adam, Doering, Travis, Wherry, E. John, Kaufmann, Daniel E., Lichterfeld, Mathias, Brass, Abraham L., Walker, Bruce D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312487/
https://ncbi.nlm.nih.gov/pubmed/25526311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.12.011
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