Redox regulation of cardiomyocyte cell cycling via an ERK1/2 and c-Myc-dependent activation of cyclin D2 transcription

Adult mammalian cardiomyocytes have a very limited capacity to proliferate, and consequently the loss of cells after cardiac stress promotes heart failure. Recent evidence suggests that administration of hydrogen peroxide (H(2)O(2)), can regulate redox-dependent signalling pathway(s) to promote card...

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Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Murray, Thomas V.A., Smyrnias, Ioannis, Schnelle, Moritz, Mistry, Rajesh K., Zhang, Min, Beretta, Matteo, Martin, Daniel, Anilkumar, Narayana, de Silva, Shana M., Shah, Ajay M., Brewer, Alison C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312357/
https://ncbi.nlm.nih.gov/pubmed/25450615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.10.017
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