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NADPH Oxidase 4 Regulates Cardiomyocyte Differentiation via Redox Activation of c-Jun Protein and the cis-Regulation of GATA-4 Gene Transcription

NADPH oxidase 4 (Nox4) generates reactive oxygen species (ROS) that can modulate cellular phenotype and function in part through the redox modulation of the activity of transcription factors. We demonstrate here the potential of Nox4 to drive cardiomyocyte differentiation in pluripotent embryonal ca...

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Hlavní autoři: Murray, Thomas V. A., Smyrnias, Ioannis, Shah, Ajay M., Brewer, Alison C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668733/
https://ncbi.nlm.nih.gov/pubmed/23589292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.439844
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