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CD47 Does Not Mediate Amyloid-β(1-42) Protofibril-Stimulated Microglial Cytokine Release
Neuroinflammation triggered by accumulation of amyloid-β protein (Aβ) is a significant component of the Alzheimer’s disease (AD) brain. Senile plaques composed of Aβ attract and activate microglia cells resulting in cytokine secretion and a proinflammatory environment. The mechanism by which Aβ acti...
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| Veröffentlicht in: | Biochem Biophys Res Commun |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312186/ https://ncbi.nlm.nih.gov/pubmed/25451248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.10.081 |
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