VEGFR3 does not sustain retinal angiogenesis without VEGFR2

Angiogenesis, the formation of new blood vessels, is regulated by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs). VEGFR2 is abundant in the tip cells of angiogenic sprouts, where VEGF/VEGFR2 functions upstream of the delta-like ligand 4 (DLL4)/Notch signal transduction path...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Zarkada, Georgia, Heinolainen, Krista, Makinen, Taija, Kubota, Yoshiaki, Alitalo, Kari
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311859/
https://ncbi.nlm.nih.gov/pubmed/25561555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423278112
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