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Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO
Deleted in colorectal cancer (DCC), a large transmembrane receptor of netrin-1, is critical for mediating netrin-1’s cardioprotective function. In the present study we investigated novel mechanisms underlying netrin-1–induced, rapid, and feed-forward up-regulation of DCC, which is believed to sustai...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4311801/ https://ncbi.nlm.nih.gov/pubmed/25561546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420695112 |
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