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Netrin-1 Prevents Ischemia/Reperfusion-induced Myocardial Infarction via a DCC/ERK1/2/eNOS(s1177)/NO/DCC Feed-forward Mechanism
We have recently shown that a novel endothelial mitogen netrin-1 potently stimulates nitric oxide (NO(•)) production via a DCC-ERK1/2 dependent mechanism. In view of the well-established cardioprotective role of NO(•), the present study investigated whether netrin-1 is cardioprotective via NO(•) sig...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866819/ https://ncbi.nlm.nih.gov/pubmed/20004665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.11.020 |
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