SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats

BACKGROUND: Diabetic patients are more sensitive to myocardial ischemic injury than non-diabetic patients. Silent information regulator 1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent histone deacetylase making the heart more resistant to ischemic injury. As SIRT1 expression is considered...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Ding, Mingge, Lei, Jingyi, Han, Hongcheng, Li, Weibo, Qu, Yinxian, Fu, Enqing, Fu, Feng, Wang, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618275/
https://ncbi.nlm.nih.gov/pubmed/26489513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0299-8
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