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Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism

Netrin-1 is critical for axonal pathfinding which shares similarities with formation of vascular network. Here we report that netrin-1 induction of angiogenesis is mediated by an increase in endothelial nitric oxide (NO(•)) production, which occurs via a DCC-dependent, ERK1/2-eNOS feed-forward mecha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nguyen, Andrew, Cai, Hua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458918/
https://ncbi.nlm.nih.gov/pubmed/16611730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511011103
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