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Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans

Transitions between asymmetric (self-renewing) and symmetric (proliferative) cell divisions are robustly regulated in the context of normal development and tissue homeostasis. To genetically assess the regulation of these transitions, we used the postembryonic epithelial stem (seam) cell lineages of...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Harandi, Omid F., Ambros, Victor R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311799/
https://ncbi.nlm.nih.gov/pubmed/25561544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422852112
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