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Whole-brain calcium imaging with cellular resolution in freely behaving Caenorhabditis elegans

The ability to acquire large-scale recordings of neuronal activity in awake and unrestrained animals is needed to provide new insights into how populations of neurons generate animal behavior. We present an instrument capable of recording intracellular calcium transients from the majority of neurons...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Nguyen, Jeffrey P., Shipley, Frederick B., Linder, Ashley N., Plummer, George S., Liu, Mochi, Setru, Sagar U., Shaevitz, Joshua W., Leifer, Andrew M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776509/
https://ncbi.nlm.nih.gov/pubmed/26712014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507110112
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