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Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses

Life history theory posits that the sequence and timing of events in an organism's lifespan are fine-tuned by evolution to maximize the production of viable offspring. In a virus, a life history strategy is largely manifested in its replication mode. Here, we develop a stochastic mathematical m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Schulte, Michael B, Draghi, Jeremy A, Plotkin, Joshua B, Andino, Raul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311501/
https://ncbi.nlm.nih.gov/pubmed/25635405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03753
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