Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia

BACKGROUND: Pediatric acute myeloid leukemia (AML) comprises up to 20% of all childhood leukemia. Recent research shows that aberrant DNA methylation patterning may play a role in leukemogenesis. The epigenetic silencing of the EBF3 locus is very frequent in glioblastoma. However, the expression pro...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Tao, Yan-Fang, Xu, Li-Xiao, Lu, Jun, Hu, Shao-Yan, Fang, Fang, Cao, Lan, Xiao, Pei-Fang, Du, Xiao-Juan, Sun, Li-Chao, Li, Zhi-Heng, Wang, Na-Na, Su, Guang-Hao, Li, Yan-Hong, Li, Gang, Zhao, He, Li, Yi-Ping, Xu, Yun-Yun, Zhou, Hui-Ting, Wu, Yi, Jin, Mei-Fang, Liu, Lin, Zhu, Xue-Ming, Ni, Jian, Wang, Jian, Xing, Feng, Zhao, Wen-Li, Pan, Jian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311429/
https://ncbi.nlm.nih.gov/pubmed/25609158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0118-1
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