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Metal-Catalyzed Azidation of Tertiary C–H Bonds Suitable for Late-Stage Functionalization

Some enzymes are able to selectively oxidize unactivated aliphatic C-H bonds to form alcohols; however biological systems do not possess enzymes that are able to catalyze the analogous amination of a C-H bond.(1,2) The absence of such chemistry is limiting because nitrogen-containing groups are foun...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Sharma, Ankit, Hartwig, John F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311404/
https://ncbi.nlm.nih.gov/pubmed/25631448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14127
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