Methylome analysis identifies a Wilms tumor epigenetic biomarker detectable in blood

BACKGROUND: Wilms tumor is the most common pediatric renal malignancy and there is a clinical need for a molecular biomarker to assess treatment response and predict relapse. The known mutated genes in this tumor type show low mutation frequencies, whereas aberrant methylation at 11p15 is by far the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Biol
Egile Nagusiak: Charlton, Jocelyn, Williams, Richard D, Weeks, Mark, Sebire, Neil J, Popov, Sergey, Vujanic, Gordan, Mifsud, William, Alcaide-German, Marisa, Butcher, Lee M, Beck, Stephan, Pritchard-Jones, Kathy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310621/
https://ncbi.nlm.nih.gov/pubmed/25134821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0434-y
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