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Methylome analysis identifies a Wilms tumor epigenetic biomarker detectable in blood
BACKGROUND: Wilms tumor is the most common pediatric renal malignancy and there is a clinical need for a molecular biomarker to assess treatment response and predict relapse. The known mutated genes in this tumor type show low mutation frequencies, whereas aberrant methylation at 11p15 is by far the...
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| Pubblicato in: | Genome Biol |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310621/ https://ncbi.nlm.nih.gov/pubmed/25134821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0434-y |
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