Chronic Hypoxemia in Late Gestation Decreases Cardiomyocyte Number but Does Not Change Expression of Hypoxia‐Responsive Genes

BACKGROUND: Placental insufficiency is the leading cause of intrauterine growth restriction in the developed world and results in chronic hypoxemia in the fetus. Oxygen is essential for fetal heart development, but a hypoxemic environment in utero can permanently alter development of cardiomyocytes....

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Botting, Kimberley J., McMillen, I. Caroline, Forbes, Heather, Nyengaard, Jens R., Morrison, Janna L.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310356/
https://ncbi.nlm.nih.gov/pubmed/25085511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000531
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