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Activation of IGF-2R stimulates cardiomyocyte hypertrophy in the late gestation sheep fetus

In vitro studies using rat and fetal sheep cardiomyocytes indicate that, in addition to its role as a clearance receptor, the insulin-like growth factor 2 receptor (IGF-2R) can induce cardiomyocyte hypertrophy. In the present study, we have determined the effect of specific activation of the IGF-2R...

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Detalhes bibliográficos
Main Authors: Wang, Kimberley C W, Brooks, Doug A, Thornburg, Kent L, Morrison, Janna L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515828/
https://ncbi.nlm.nih.gov/pubmed/22930271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.238410
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