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Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus

It is unknown whether cardiomyocyte hypertrophy and the transition to fatty acid oxidation as the main source of energy after birth is dependent on the maturation of the cardiomyocytes' metabolic system, or on the limitation of substrate availability before birth. This study aimed to investigat...

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Bibliografische gegevens
Hoofdauteurs: Lie, Shervi, Hui, Melisa, McMillen, I. Caroline, Muhlhausler, Beverly S., Posterino, Giuseppe S., Dunn, Stacey L., Wang, Kimberley C., Botting, Kimberley J., Morrison, Janna L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949109/
https://ncbi.nlm.nih.gov/pubmed/24477540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00431.2013
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