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Hydrogen-deuterium exchange of aromatic amines and amides using deuterated trifluoroacetic acid
The H-D exchange of aromatic amines and amides, including pharmaceutically relevant compounds such as acetaminophen and diclofenac, was investigated using CF(3)COOD as both the sole reaction solvent and source of deuterium label. The described method is amenable to efficient deuterium incorporation...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310004/ https://ncbi.nlm.nih.gov/pubmed/25641994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.12.102 |
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