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Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases

The development of in vitro amplification systems allows detecting femtomolar amounts of prion protein scrapie (PrP(Sc)) in human cerebrospinal fluid (CSF). We performed a CSF study to determine the effects of prion disease type, codon 129 genotype, PrP(Sc) type, and other disease-related factors on...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Cramm, Maria, Schmitz, Matthias, Karch, André, Zafar, Saima, Varges, Daniela, Mitrova, Eva, Schroeder, Bjoern, Raeber, Alex, Kuhn, Franziska, Zerr, Inga
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309904/
https://ncbi.nlm.nih.gov/pubmed/24809690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8709-6
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