Astrocyte elevated gene-1 (AEG-1) and c-Myc cooperate to promote hepatocarcinogenesis

Astrocyte elevated gene-1 (AEG-1) and c-Myc are overexpressed in human hepatocellular carcinoma (HCC) functioning as oncogenes. AEG-1 is transcriptionally regulated by c-Myc and AEG-1 itself induces c-Myc by activating Wnt/β-catenin signaling pathway. We now document cooperation of AEG-1 and c-Myc i...

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Publicat a:Hepatology
Autors principals: Srivastava, Jyoti, Siddiq, Ayesha, Gredler, Rachel, Shen, Xue-Ning, Rajasekaran, Devaraja, Robertson, Chadia L., Subler, Mark A., Windle, Jolene J., Dumur, Catherine I., Mukhopadhyay, Nitai D., Garcia, Dawn, Lai, Zhao, Chen, Yidong, Balaji, Uthra, Fisher, Paul B., Sarkar, Devanand
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309751/
https://ncbi.nlm.nih.gov/pubmed/25065684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27339
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