Distinguishing Regulatory DNA From Neutral Sites

We explore several computational approaches to analyzing interspecies genomic sequence alignments, aiming to distinguish regulatory regions from neutrally evolving DNA. Human–mouse genomic alignments were collected for three sets of human regions: (1) experimentally defined gene regulatory regions,...

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Main Authors: Elnitski, Laura, Hardison, Ross C., Li, Jia, Yang, Shan, Kolbe, Diana, Eswara, Pallavi, O'Connor, Michael J., Schwartz, Scott, Miller, Webb, Chiaromonte, Francesca
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2003
Teme:
Letters
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC430974/
https://ncbi.nlm.nih.gov/pubmed/12529307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.817703
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