Distinguishing Regulatory DNA From Neutral Sites

We explore several computational approaches to analyzing interspecies genomic sequence alignments, aiming to distinguish regulatory regions from neutrally evolving DNA. Human–mouse genomic alignments were collected for three sets of human regions: (1) experimentally defined gene regulatory regions,...

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Main Authors: Elnitski, Laura, Hardison, Ross C., Li, Jia, Yang, Shan, Kolbe, Diana, Eswara, Pallavi, O'Connor, Michael J., Schwartz, Scott, Miller, Webb, Chiaromonte, Francesca
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2003
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Letters
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC430974/
https://ncbi.nlm.nih.gov/pubmed/12529307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.817703
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