Distinguishing Regulatory DNA From Neutral Sites

We explore several computational approaches to analyzing interspecies genomic sequence alignments, aiming to distinguish regulatory regions from neutrally evolving DNA. Human–mouse genomic alignments were collected for three sets of human regions: (1) experimentally defined gene regulatory regions,...

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Detalhes bibliográficos
Main Authors: Elnitski, Laura, Hardison, Ross C., Li, Jia, Yang, Shan, Kolbe, Diana, Eswara, Pallavi, O'Connor, Michael J., Schwartz, Scott, Miller, Webb, Chiaromonte, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
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Letters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430974/
https://ncbi.nlm.nih.gov/pubmed/12529307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.817703
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