Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN

The evolutionarily conserved IGF-1 signalling pathway is associated with longevity, metabolism, tissue homeostasis, and cancer progression. Its regulation relies on the delicate balance between activating kinases and suppressing phosphatases and is still not very well understood. We report here that...

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Detaylı Bibliyografya
Yayımlandı:EMBO Mol Med
Asıl Yazarlar: Singh, Karmveer, Maity, Pallab, Krug, Linda, Meyer, Patrick, Treiber, Nicolai, Lucas, Tanja, Basu, Abhijit, Kochanek, Stefan, Wlaschek, Meinhard, Geiger, Hartmut, Scharffetter-Kochanek, Karin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309668/
https://ncbi.nlm.nih.gov/pubmed/25520316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404082
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