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Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN
The evolutionarily conserved IGF-1 signalling pathway is associated with longevity, metabolism, tissue homeostasis, and cancer progression. Its regulation relies on the delicate balance between activating kinases and suppressing phosphatases and is still not very well understood. We report here that...
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| Publicado no: | EMBO Mol Med |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309668/ https://ncbi.nlm.nih.gov/pubmed/25520316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404082 |
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