Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma

Melanoma is the most fatal skin cancer, but the etiology of this devastating disease is still poorly understood. Recently, the transcription factor Sox10 has been shown to promote both melanoma initiation and progression. Reducing SOX10 expression levels in human melanoma cells and in a genetic mela...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Shakhova, Olga, Cheng, Phil, Mishra, Pravin J., Zingg, Daniel, Schaefer, Simon M., Debbache, Julien, Häusel, Jessica, Matter, Claudia, Guo, Theresa, Davis, Sean, Meltzer, Paul, Mihic-Probst, Daniela, Moch, Holger, Wegner, Michael, Merlino, Glenn, Levesque, Mitchell P., Dummer, Reinhard, Santoro, Raffaella, Cinelli, Paolo, Sommer, Lukas
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309598/
https://ncbi.nlm.nih.gov/pubmed/25629959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004877
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