Hedgehog-Gli activation during rhabdomyosarcoma genesis in postnatal mice

Dysregulation of the Hedgehog (Hh)-Gli signaling pathway is implicated in a variety of human cancers, including basal cell carcinoma (BCC), medulloblastoma (MB), and embryonal rhabdhomyosarcoma (eRMS), three principle tumors associated with human Gorlin syndrome. However, the cellular origins of the...

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Udgivet i:Oncogene
Main Authors: Rajurkar, Mihir, Huang, He, Cotton, Jennifer L., Brooks, Julie K., Sicklick, Jason, McMahon, Andrew P., Mao, Junhao
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309268/
https://ncbi.nlm.nih.gov/pubmed/24276242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.480
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