Hedgehog-Gli Pathway Activation during Kidney Fibrosis

The Hedgehog (Hh) signaling pathway regulates tissue patterning during development, including patterning and growth of limbs and face, but whether Hh signaling plays a role in adult kidney remains undefined. In this study, using a panel of hedgehog-reporter mice, we show that the two Hh ligands (Ind...

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Detalhes bibliográficos
Main Authors: Fabian, Steven L., Penchev, Radostin R., St-Jacques, Benoit, Rao, Anjali N., Sipilä, Petra, West, Kip A., McMahon, Andrew P., Humphreys, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349903/
https://ncbi.nlm.nih.gov/pubmed/22342522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.12.039
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