Comparative Analysis of Vertebrate Dystrophin Loci Indicate Intron Gigantism as a Common Feature

The human DMD gene is the largest known to date, spanning > 2000 kb on the X chromosome. The gene size is mainly accounted for by huge intronic regions. We sequenced 190 kb of Fugu rubripes (pufferfish) genomic DNA corresponding to the complete dystrophin gene (FrDMD) and provide the first report...

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Bibliographic Details
Main Authors: Pozzoli, Uberto, Elgar, Greg, Cagliani, Rachele, Riva, Laura, Comi, Giacomo P., Bresolin, Nereo, Bardoni, Alessandra, Sironi, Manuela
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC430921/
https://ncbi.nlm.nih.gov/pubmed/12727896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.776503
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