Prospective Validation Obtained in a Similar Group of Patients and with Similar High Throughput Biological Tests Failed to Confirm Signatures for Prediction of Response to Chemotherapy and Survival in Advanced NSCLC: A Prospective Study from the European Lung Cancer Working Party

Aim: Cisplatin doublets are standard 1st line treatment for advanced non-small cell lung cancer (NSCLC), without accurate predictor for response and survival, but important toxicity. Our aims were to identify predictive (for response) and prognostic (for survival) biological signatures in patients w...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Berghmans, Thierry, Ameye, Lieveke, Lafitte, Jean-Jacques, Colinet, Benoît, Cortot, Alexis, CsToth, Ingrid, Holbrechts, Stéphane, Lecomte, Jacques, Mascaux, Céline, Meert, Anne-Pascale, Paesmans, Marianne, Richez, Michel, Scherpereel, Arnaud, Tulippe, Christian, Willems, Luc, Dernies, Tiffany, Leclercq, Nathalie, Sculier, Jean-Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309174/
https://ncbi.nlm.nih.gov/pubmed/25674536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00386
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