Prospective Validation Obtained in a Similar Group of Patients and with Similar High Throughput Biological Tests Failed to Confirm Signatures for Prediction of Response to Chemotherapy and Survival in Advanced NSCLC: A Prospective Study from the European Lung Cancer Working Party

Aim: Cisplatin doublets are standard 1st line treatment for advanced non-small cell lung cancer (NSCLC), without accurate predictor for response and survival, but important toxicity. Our aims were to identify predictive (for response) and prognostic (for survival) biological signatures in patients w...

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Vydáno v:Front Oncol
Hlavní autoři: Berghmans, Thierry, Ameye, Lieveke, Lafitte, Jean-Jacques, Colinet, Benoît, Cortot, Alexis, CsToth, Ingrid, Holbrechts, Stéphane, Lecomte, Jacques, Mascaux, Céline, Meert, Anne-Pascale, Paesmans, Marianne, Richez, Michel, Scherpereel, Arnaud, Tulippe, Christian, Willems, Luc, Dernies, Tiffany, Leclercq, Nathalie, Sculier, Jean-Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309174/
https://ncbi.nlm.nih.gov/pubmed/25674536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00386
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