VAC chemotherapy with valproic acid for refractory/relapsing small cell lung cancer: a phase II study

Salvage chemotherapy (CT) for relapsing or refractory small cell lung cancer (SCLC) remains disappointing. In vitro experiments showed that valproic acid increases apoptosis of SCLC cell lines exposed to doxorubicin, vindesine and bis(2-chloroethyl)amine. The primary objective of this phase II study...

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Detalhes bibliográficos
Publicado no:ERJ Open Res
Principais autores: Berghmans, Thierry, Lafitte, Jean-Jacques, Scherpereel, Arnaud, Ameye, Lieveke, Paesmans, Marianne, Meert, Anne-Pascale, Colinet, Benoit, Tulippe, Christian, Willems, Luc, Leclercq, Nathalie, Sculier, Jean-Paul
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005117/
https://ncbi.nlm.nih.gov/pubmed/27730152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00029-2015
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