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The Potential of panHER Inhibition in Cancer
Purpose: Hyper-activation of the HER (erbB) family receptors, HER 1-4, leads to up-regulation of the three vital signaling pathways: mitogen activated protein kinase, phosphoinositide 3-kinase/AKT, and Janus kinase/signal transducer and activator of transcription pathways. Blocking HER1/EGFR has a l...
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| Pubblicato in: | Front Oncol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309158/ https://ncbi.nlm.nih.gov/pubmed/25674538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00002 |
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