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Identification of Fumarate Hydratase Inhibitors with Nutrient-Dependent Cytotoxicity
[Image: see text] Development of cell-permeable small molecules that target enzymes involved in energy metabolism remains important yet challenging. We describe here the discovery of a new class of compounds with a nutrient-dependent cytotoxicity profile that arises from pharmacological inhibition o...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4308746/ https://ncbi.nlm.nih.gov/pubmed/25469852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5101257 |
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