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Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia
Cancer is a clonal evolutionary process, caused by successive accumulation of genetic alterations providing milestones of tumor initiation, progression, dissemination, and/or resistance to certain therapeutic regimes. To unravel these milestones we propose a framework, tumor evolutionary directed gr...
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發表在: | eLife |
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Main Authors: | , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
eLife Sciences Publications, Ltd
2014
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4308685/ https://ncbi.nlm.nih.gov/pubmed/25496728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02869 |
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