Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia

Cancer is a clonal evolutionary process, caused by successive accumulation of genetic alterations providing milestones of tumor initiation, progression, dissemination, and/or resistance to certain therapeutic regimes. To unravel these milestones we propose a framework, tumor evolutionary directed gr...

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Gepubliceerd in:eLife
Hoofdauteurs: Wang, Jiguang, Khiabanian, Hossein, Rossi, Davide, Fabbri, Giulia, Gattei, Valter, Forconi, Francesco, Laurenti, Luca, Marasca, Roberto, Del Poeta, Giovanni, Foà, Robin, Pasqualucci, Laura, Gaidano, Gianluca, Rabadan, Raul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2014
Onderwerpen:
Genomics and Evolutionary Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308685/
https://ncbi.nlm.nih.gov/pubmed/25496728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02869
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