Epigenetic Changes of EGFR play an important role in BRAF inhibitor Resistant Cutaneous Melanomas

BRAF mutations are frequent in cutaneous melanomas and BRAF inhibitors(BRAFi) have shown remarkable clinical efficacy in BRAF mutant melanoma patients. However, acquired drug resistance can occur rapidly and tumor(s) often progress thereafter. Various mechanisms of BRAFi resistance have recently bee...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Invest Dermatol
मुख्य लेखकों: Wang, Jinhua, Huang, Sharon K., Marzese, Diego M., Hsu, Sandy C., Kawas, Neal P., Chong, Kelly K., Long, Georgina V., Menzies, Alexander M., Scolyer, Richard A., Izraely, Sivan, Sagi-Assif, Orit, Witz, Isaac P., Hoon, Dave S.B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307785/
https://ncbi.nlm.nih.gov/pubmed/25243790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.418
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