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Cystatin C takes part in melanoma-microglia cross-talk: possible implications for brain metastasis

The development of melanoma brain metastasis is largely dependent on mutual interactions between the melanoma cells and cells in the brain microenvironment. Here, we report that the extracellular cysteine protease inhibitor cystatin C (CysC) is involved in these interactions. Microglia-derived facto...

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Detalhes bibliográficos
Publicado no:Clin Exp Metastasis
Main Authors: Moshe, Adi, Izraely, Sivan, Sagi-Assif, Orit, Prakash, Roshini, Telerman, Alona, Meshel, Tsipi, Carmichael, Thomas, Witz, Isaac P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208992/
https://ncbi.nlm.nih.gov/pubmed/29722001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-018-9891-0
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