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Cellular uptake and nuclear binding of insulin in human cultured lymphocytes: evidence for potential intracellular sites of insulin action.

Human cultured lymphocytes (IM-9) were used to demonstrate that insulin can enter the intact cell and bind to the nucleus. When these lymphocytes were incubated with 125I-labeled insulin, specific cellular uptake reached a maximum within 2 min and remained at a plateau for 90 min or longer. Partiall...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Goldfine, I D, Smith, G J, Wong, K Y, Jones, A L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1977
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC430761/
https://ncbi.nlm.nih.gov/pubmed/193098
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