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Vitamin K-dependent synthesis and modification of precursor prothrombin in cultured H-35 hepatoma cells.
The ability of confluent monolayers of H-35 cells, originally obtained from a rat hepatoma, to synthesize prothrombin in response to vitamin K1 (phylloquinone) was studied. As demonstrated by radioimmunoassay, selective barium salt adsorption, and two coagulation assays which discriminate between pr...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1976
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/183212/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.8.2803 |
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