Vitamin K-dependent synthesis and modification of precursor prothrombin in cultured H-35 hepatoma cells.

The ability of confluent monolayers of H-35 cells, originally obtained from a rat hepatoma, to synthesize prothrombin in response to vitamin K1 (phylloquinone) was studied. As demonstrated by radioimmunoassay, selective barium salt adsorption, and two coagulation assays which discriminate between pr...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Munns, T W, Johnston, M F, Liszewski, M K, Olson, R E
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1976
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/183212/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.8.2803
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