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Mechanism of Action of Vitamin K: Evidence for the Conversion of a Precursor Protein to Prothrombin in the Rat

Previous studies have shown that the vitamin K-induced synthesis of prothrombin in a vitamin K-deficient rat is only slightly inhibited by cycloheximide treatment. Rat prothrombin has now been purified by disc electrophoresis after BaSO(4) adsorption and citrate elution. When cycloheximide (5 mg/kg)...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Shah, D. V., Suttie, J. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1971
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389261/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5283959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.7.1653
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