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Mechanism of Action of Vitamin K: Evidence for the Conversion of a Precursor Protein to Prothrombin in the Rat

Previous studies have shown that the vitamin K-induced synthesis of prothrombin in a vitamin K-deficient rat is only slightly inhibited by cycloheximide treatment. Rat prothrombin has now been purified by disc electrophoresis after BaSO(4) adsorption and citrate elution. When cycloheximide (5 mg/kg)...

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Detalhes bibliográficos
Main Authors: Shah, D. V., Suttie, J. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC389261/
https://ncbi.nlm.nih.gov/pubmed/5283959
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